Name: AM-3102
Rating: 5 (10 reviews)

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HIT ID:HIT212714635
Cas No:213182-22-0
常用名:AM-3102
别名:Methyl oleoylethanolamide, KDS-5104, AM 3102
别名:Methyl oleoylethanolamide, KDS-5104, AM 3102
IUPAC:(9Z)-N-[(2R)-1-hydroxypropan-2-yl]octadec-9-enamide
IUPAC:(9Z)-N-[(2R)-1-hydroxypropan-2-yl]octadec-9-enamide
InChI key:IPVYNYWIRWMRHH-JPMGXVIASA-N

分子式:C21H41NO2
分子量:339.564
氢键供体数 (HBD):2
氢键受体数 (HBA):2
LogP:5.927005
SMILES:CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](C)CO
SMILES:CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](C)CO

AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.

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