Evogliptin HCl | Evogliptin hydrochloride | Evogliptin | DA-1229 | DA1229 | DA 1229 | CAS 1246960-27-9 | AnyMole

有库存

HIT212716048

sdf 文件

结构编辑

类似物检索

HIT212716048

HIT ID:HIT212716048
Cas No:1246960-27-9
常用名:Evogliptin HCl
别名:Evogliptin hydrochloride, Evogliptin, DA-1229, DA1229, DA 1229
别名:Evogliptin hydrochloride, Evogliptin, DA-1229, DA1229, DA 1229
IUPAC:(3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(tert-butoxy)methyl]piperazin-2-one hydrochloride
IUPAC:(3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(tert-butoxy)methyl]piperazin-2-one hydrochloride
InChI key:QHQXWMKKQNSBTC-VQZRABBESA-N

分子式:C19H27ClF3N3O3
分子量:437.89
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:1.1730862
SMILES:Cl.CC(C)(C)OC[C@H]1N(CCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F
SMILES:Cl.CC(C)(C)OC[C@H]1N(CCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

Evogliptin(DA-1229) is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) that can improve insulin resistance and delays the onset of diabetes. Evogliptin delays the onset of diabetes in young db/db mice and improves insulin sensitivity in HF mice.

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供应商
TargetMolSC
规格
货期
6-8周
纯度
-
¥ 10,600.00
1

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