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  3. HIT212716130
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HIT212716130
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HIT212716130
  • HIT ID:HIT212716130
  • Cas No:1054629-49-0
  • 常用名:AZD4694
  • 别名:NAV-4694, NAV4694, NAV 4694, Flutafuranol, AZD-4694, AZD 4694
    别名:NAV-4694, NAV4694, NAV 4694, Flutafuranol, AZD-4694, AZD 4694
  • IUPAC:2-[2-fluoro-6-(methylamino)pyridin-3-yl]-1-benzofuran-5-ol
    IUPAC:2-[2-fluoro-6-(methylamino)pyridin-3-yl]-1-benzofuran-5-ol
  • InChI key:MYNQXTDIPMCJCR-UHFFFAOYSA-N
  • 分子式:C14H11FN2O2
  • 分子量:258.252
  • 氢键供体数 (HBD):2
  • 氢键受体数 (HBA):3
  • LogP:2.7822263
  • SMILES:CNc1ccc(-c2cc3cc(O)ccc3o2)c(F)n1
    SMILES:CNc1ccc(-c2cc3cc(O)ccc3o2)c(F)n1
  • Flutafuranol, also known as AZD 4694 and NAV4694, is a bio-active chemical. AZD4694 shows high affinity for beta-amyloid fibrils in vitro (K(d) = 2.3 +/- 0.3 nM). The fluorine-18 labeled AZD4694 may have potential for PET-visualization of cerebral beta-amyloid deposits in the living human brain. (18)F-AZD4694 satisfies the requirements for a promising amyloid-β radioligand both for diagnostic use and for evaluation of disease-modifying therapies in AD. Note: Flutafuranol we will supply is not a F18-label chemical.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    5日内发货
    纯度
    -
    ¥ 9,890.00
    1

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