• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT212717309
有库存
HIT212717309
 sdf 文件
结构编辑
类似物检索
HIT212717309
  • HIT ID:HIT212717309
  • Cas No:129716-45-6
  • 常用名:MS-073
  • 别名:MS 073, CP-162398, CP162398, CP 162398
  • IUPAC:1-(quinolin-5-yloxy)-3-(4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}piperazin-1-yl)propan-2-ol
    IUPAC:1-(quinolin-5-yloxy)-3-(4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}piperazin-1-yl)propan-2-ol
  • InChI key:YLQSXCMKFKBZLE-UHFFFAOYSA-N
  • 分子式:C31H33N3O2
  • 分子量:479.624
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):5
  • LogP:5.822
  • SMILES:OC(COc1cccc2ncccc12)CN1CCN(CC1)C1c2ccccc2CCc2ccccc12
    SMILES:OC(COc1cccc2ncccc12)CN1CCN(CC1)C1c2ccccc2CCc2ccccc12
  • MS-073 (CP-162398) is a P-glycoprotein inhibitor (P-gp). The in vitro resistance to vincristine (VCR) was almost completely reversed in VCR-resistant P388 cells, and the resistance of VCR, adriamycin (ADM), etoposide, and actinomycin D in ADM-resistant human myeloid leukemia K562 (K562/ADM) cells in vitro was also reversed. MS-073 reverses MDR by competitively inhibiting the binding of drugs to P-glycoprotein.
市场产品/服务共显示3个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1
  • 供应商
    EnamineBB
    规格
    货期
    4-6周
    纯度
    -
    ¥ 10,560.00
    1
  • 供应商
    EnamineSC
    规格
    货期
    4-6周
    纯度
    -
    ¥ 1,830.00
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层