PBOX-15 | CAS 354759-10-7 | AnyMole

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HIT212717600

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HIT212717600

HIT ID:HIT212717600
Cas No:354759-10-7
常用名:PBOX-15
IUPAC:8-(naphthalen-1-yl)-9-oxa-2-azatetracyclo[8.8.0.0^{2,6}.0^{12,17}]octadeca-1(18),3,5,7,10,12,14,16-octaen-7-yl acetate
IUPAC:8-(naphthalen-1-yl)-9-oxa-2-azatetracyclo[8.8.0.0^{2,6}.0^{12,17}]octadeca-1(18),3,5,7,10,12,14,16-octaen-7-yl acetate
InChI key:STVDRIIZTGYIMM-UHFFFAOYSA-N

分子式:C28H19NO3
分子量:417.464
氢键供体数 (HBD):0
氢键受体数 (HBA):2
LogP:5.4078994
SMILES:CC(=O)OC1=C(Oc2cc3ccccc3cc2-n2cccc12)c1cccc2ccccc12 |t:4|
SMILES:CC(=O)OC1=C(Oc2cc3ccccc3cc2-n2cccc12)c1cccc2ccccc12 |t:4|

PBOX-15 is a novel microtubule-targeting agent that induces apoptosis, upregulates death receptors, and enhances TRAIL-mediated apoptosis in multiple myeloma cells. It also inhibits T cell migration through post-translational modification of tubulin. Pbox-15 induced apoptosis, up-regulated death receptors, and enhanced TRAIL-mediated apoptosis in multiple myeloma cells.

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TargetMolSC
规格
货期
6-8周
纯度
-
¥ 11,700.00
1

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