Name: Samelisant dihydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT212718367
Cas No:1394808-20-8
常用名:Samelisant dihydrochloride
别名:SUVN-G3031 HCl, SUVN-G3031 2HCl, SUVN-G 3031 HCl, SUVN G3031 HCl
别名:SUVN-G3031 HCl, SUVN-G3031 2HCl, SUVN-G 3031 HCl, SUVN G3031 HCl
IUPAC:N-{4-[(1-cyclobutylpiperidin-4-yl)oxy]phenyl}-2-(morpholin-4-yl)acetamide dihydrochloride
IUPAC:N-{4-[(1-cyclobutylpiperidin-4-yl)oxy]phenyl}-2-(morpholin-4-yl)acetamide dihydrochloride
InChI key:LCPQCTBHZPMVFX-UHFFFAOYSA-N

分子式:C21H33Cl2N3O3
分子量:446.41
氢键供体数 (HBD):1
氢键受体数 (HBA):5
LogP:1.6632223
SMILES:Cl.Cl.O=C(CN1CCOCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1
SMILES:Cl.Cl.O=C(CN1CCOCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1

Samelisant dihydrochloride (SUVN-G3031) is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating disorders, and pain.

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