• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT212723339
有库存
HIT212723339
 sdf 文件
结构编辑
类似物检索
HIT212723339
  • HIT ID:HIT212723339
  • Cas No:288144-20-7
  • 常用名:VEGFR2 Kinase Inhibitor II
  • IUPAC:(3Z)-5-bromo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
    IUPAC:(3Z)-5-bromo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
  • InChI key:RFHPWPWVGFSLOP-ZROIWOOFSA-N
  • 分子式:C17H15BrN2O
  • 分子量:343.224
  • 氢键供体数 (HBD):2
  • 氢键受体数 (HBA):1
  • LogP:4.250216
  • SMILES:Brc1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1
    SMILES:Brc1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1
  • Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2's kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor β (PDGFRβ; IC50 = 920 nM) and related receptor and non-receptor tyrosine kinases. VEGFR2 kinase inhibitor II blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50s = 110 nM and 2 μM, respectively).
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 3,920.00
    1
  • 供应商
    AA BlocksBB
    规格
    货期
    4-6周
    纯度
    -
    待询
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层