Name: S-Acetyl-L-glutathione
Rating: 5 (10 reviews)

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HIT ID:HIT212723474
Cas No:3054-47-5
常用名:S-Acetyl-L-glutathione
IUPAC:(2S)-4-{[(1R)-2-(acetylsulfanyl)-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}-2-aminobutanoic acid
IUPAC:(2S)-4-{[(1R)-2-(acetylsulfanyl)-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}-2-aminobutanoic acid
InChI key:FVRWSIPJNWXCEO-YUMQZZPRSA-N

分子式:C12H19N3O7S
分子量:349.36
氢键供体数 (HBD):5
氢键受体数 (HBA):8
LogP:-5.064935
SMILES:CC(=O)SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
SMILES:CC(=O)SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O

S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases survival in a mouse model of HSV-1 infection.

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