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HIT212728945
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HIT212728945
  • HIT ID:HIT212728945
  • Cas No:1254277-89-8
  • 常用名:Termitomycamide B
  • IUPAC:(9Z,12Z)-N-[2-(1H-indol-2-yl)-2-oxoethyl]octadeca-9,12-dienamide
    IUPAC:(9Z,12Z)-N-[2-(1H-indol-2-yl)-2-oxoethyl]octadeca-9,12-dienamide
  • InChI key:KDZGHQVBEWMXHZ-HZJYTTRNSA-N
  • 分子式:C28H40N2O2
  • 分子量:436.64
  • 氢键供体数 (HBD):2
  • 氢键受体数 (HBA):2
  • LogP:7.089596
  • SMILES:CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCC(=O)c1cc2ccccc2[nH]1
    SMILES:CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCC(=O)c1cc2ccccc2[nH]1
  • Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson's, Alzheimer's, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,080.00
    1
  • 供应商
    AA BlocksBB
    规格
    货期
    4-6周
    纯度
    -
    待询
    1

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