Name: (±)-Clopidogrel (hydrochloride)
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212729395
Cas No:130209-90-4
常用名:(±)-Clopidogrel (hydrochloride)
IUPAC:methyl 2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate hydrochloride
IUPAC:methyl 2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate hydrochloride
InChI key:XIHVAFJSGWDBGA-UHFFFAOYSA-N

分子式:C16H17Cl2NO2S
分子量:358.28
氢键供体数 (HBD):0
氢键受体数 (HBA):2
LogP:4.031764
SMILES:Cl.COC(=O)C(N1CCc2sccc2C1)c1ccccc1Cl
SMILES:Cl.COC(=O)C(N1CCc2sccc2C1)c1ccccc1Cl

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix , clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascular ischemic events for patients without deficiencies in CYP2C19-related metabolism.

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~