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  3. HIT212731923
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HIT212731923
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HIT212731923
  • HIT ID:HIT212731923
  • Cas No:564-87-4
  • 常用名:11-cis Retinal
  • IUPAC:(2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
    IUPAC:(2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
  • InChI key:NCYCYZXNIZJOKI-IOUUIBBYSA-N
  • 分子式:C20H28O
  • 分子量:284.443
  • 氢键供体数 (HBD):0
  • 氢键受体数 (HBA):1
  • LogP:4.8557515
  • SMILES:C/C(/C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C\C=O |c:9|
    SMILES:C/C(/C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C\C=O |c:9|
  • 11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    3-6月
    纯度
    -
    ¥ 117,550.00
    1
  • 供应商
    AA BlocksBB
    规格
    货期
    4-6周
    纯度
    -
    待询
    1

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