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HIT212732682
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HIT212732682
  • HIT ID:HIT212732682
  • Cas No:878627-21-5
  • 常用名:N-tridecanoyl-L-Homoserine lactone
    常用名:N-tridecanoyl-L-Homoserine lactone
  • IUPAC:N-[(3S)-2-oxooxolan-3-yl]tridecanamide
    IUPAC:N-[(3S)-2-oxooxolan-3-yl]tridecanamide
  • InChI key:BWHZLNSEWMAGNV-HNNXBMFYSA-N
  • 分子式:C17H31NO3
  • 分子量:297.439
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):2
  • LogP:4.0638785
  • SMILES:CCCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
    SMILES:CCCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
  • Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. N-tridecanoyl-L-Homoserine lactone (C13-HSL) possesses a rare odd-numbered acyl carbon chain and is produced by wild-type and mutant strains of Y. pseudotuberculosis in trace amounts.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
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    ¥ 1,080.00
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  • 供应商
    AA BlocksBB
    规格
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    4-6周
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