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  3. HIT212742605
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HIT212742605
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HIT212742605
  • HIT ID:HIT212742605
  • Cas No:189894-79-9
  • 常用名:C6 D-threo Ceramide (d18:1/6:0)
  • 别名:C6 D-threo Ceramide (d18:1/6:0)
  • IUPAC:N-[(2R,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]hexanamide
    IUPAC:N-[(2R,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]hexanamide
  • InChI key:NPRJSFWNFTXXQC-KHZUJUORSA-N
  • 分子式:C24H47NO3
  • 分子量:397.644
  • 氢键供体数 (HBD):3
  • 氢键受体数 (HBA):3
  • LogP:6.4196687
  • SMILES:CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](CO)NC(=O)CCCCC
    SMILES:CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](CO)NC(=O)CCCCC
  • C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater than 5 μM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.
市场产品/服务共显示2个结果
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    TargetMolSC
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    ¥ 4,254.00
    1
  • 供应商
    AA BlocksBB
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    4-6周
    纯度
    -
    待询
    1

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