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HIT212742627
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HIT212742627
  • HIT ID:HIT212742627
  • Cas No:143615-69-4
  • 常用名:C2 L-threo Ceramide (d18:1/2:0)
  • 别名:C2 L-threo Ceramide (d18:1/2:0)
  • IUPAC:N-[(2S,3S,4E)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide
    IUPAC:N-[(2S,3S,4E)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide
  • InChI key:BLTCBVOJNNKFKC-LOVRKWTRSA-N
  • 分子式:C20H39NO3
  • 分子量:341.536
  • 氢键供体数 (HBD):3
  • 氢键受体数 (HBA):3
  • LogP:4.3854265
  • SMILES:CCCCCCCCCCCCC\C=C\[C@H](O)[C@H](CO)NC(C)=O
    SMILES:CCCCCCCCCCCCC\C=C\[C@H](O)[C@H](CO)NC(C)=O
  • C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
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    货期
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    -
    ¥ 2,417.00
    1
  • 供应商
    AA BlocksBB
    规格
    货期
    4-6周
    纯度
    -
    待询
    1

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