Name: 17α,20β-Dihydroxy-4-pregnen-3-one
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212760805
Cas No:1662-06-2
常用名:17α,20β-Dihydroxy-4-pregnen-3-one
常用名:17α,20β-Dihydroxy-4-pregnen-3-one
别名:17α,20β-Dihydroxy-4-pregnen-3-one, 17α,20β-dihydroxy Progesterone, 17α,20β-DHP
别名:17α,20β-Dihydroxy-4-pregnen-3-one, 17α,20β-dihydroxy Progesterone, 17α,20β-DHP
IUPAC:(1R,3aS,3bR,9aR,9bS,11aS)-1-hydroxy-1-[(1R)-1-hydroxyethyl]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
IUPAC:(1R,3aS,3bR,9aR,9bS,11aS)-1-hydroxy-1-[(1R)-1-hydroxyethyl]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
InChI key:MASCESDECGBIBB-FSHQYNQFSA-N

分子式:C21H32O3
分子量:332.484
氢键供体数 (HBD):2
氢键受体数 (HBA):3
LogP:3.015665
SMILES:C[C@@H](O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |t:11|
SMILES:C[C@@H](O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |t:11|

17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persian sturgeon oocytes has been shown to effectively induce germinal vesicle breakdown, an essential step during oocyte maturation.1 Gonadotropin-releasing hormone and the gonadotropins, follicle-stimulating hormone and luteinizing hormone, have been shown to stimulate the production of 17α,20β-DHP either in vivo or in vitro.[2] 17α,20β-DHP has also been reported to influence spermiation by stimulating milt production when administered at 5 mg/kg to various male teleosts.[1]

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~