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  3. HIT212761371
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HIT212761371
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HIT212761371
  • HIT ID:HIT212761371
  • Cas No:152013-26-8
  • 常用名:Des-4-fluorobenzyl Mosapride
  • 别名:Des-p-fluorobenzyl Mosapride
  • IUPAC:4-amino-5-chloro-2-ethoxy-N-[(morpholin-2-yl)methyl]benzamide
    IUPAC:4-amino-5-chloro-2-ethoxy-N-[(morpholin-2-yl)methyl]benzamide
  • InChI key:HQOQHUQAQLNFOP-UHFFFAOYSA-N
  • 分子式:C14H20ClN3O3
  • 分子量:313.78
  • 氢键供体数 (HBD):3
  • 氢键受体数 (HBA):5
  • LogP:0.4986808
  • SMILES:CCOc1cc(N)c(Cl)cc1C(=O)NCC1CNCCO1
    SMILES:CCOc1cc(N)c(Cl)cc1C(=O)NCC1CNCCO1
  • Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    8-10周
    纯度
    -
    待询
    1
  • 供应商
    AA BlocksBB
    规格
    货期
    4-6周
    纯度
    -
    待询
    1

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