Name: Calpain Inhibitor-1
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212972257
Cas No:1448429-06-8
常用名:Calpain Inhibitor-1
IUPAC:(2S,3S)-3-{[(1S)-1-({[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]methyl}carbamoyl)-2-(1,3-thiazol-4-yl)ethyl]carbamoyl}oxirane-2-carboxylic acid
IUPAC:(2S,3S)-3-{[(1S)-1-({[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]methyl}carbamoyl)-2-(1,3-thiazol-4-yl)ethyl]carbamoyl}oxirane-2-carboxylic acid
InChI key:IPWMYOJQVHCYRC-JYJNAYRXSA-N

分子式:C19H17FN6O5S
分子量:460.44
氢键供体数 (HBD):3
氢键受体数 (HBA):8
LogP:-0.05094312
SMILES:OC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](Cc1cscn1)C(=O)NCc1cn(nn1)-c1ccc(F)cc1
SMILES:OC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](Cc1cscn1)C(=O)NCc1cn(nn1)-c1ccc(F)cc1

Calpain Inhibitor-1 (compound 36) is a highly potent and selective inhibitor of Calpain 1 (Cal1), which is a cysteine protease. It exhibits an IC50 value of 100 nM and a Ki value of 2.89 μM.

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymol随时为您提供帮助。

电话：400-820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~