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- HIT ID:HIT213127020
- Cas No:111625-28-6
- 别名:(2-pyridyldithio)-PEG1-hydrazine
- InChI key:PORTXTUJPQINJC-UHFFFAOYSA-N
- 分子式:C7H9NOS2
- 分子量:187.28
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- (2-Pyridyldithio)-PEG1-hydrazine is a one-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This linker offers the advantage of controlled release of the drug payload from the ADC construct. It is utilized in the conjugation process between the antibody and the cytotoxic drug, enabling the targeted delivery of the drug to cancer cells. The (2-pyridyldithio) group of this linker provides stability during circulation in the bloodstream, while the hydrazine moiety allows for efficient drug release at the tumor site. Overall, the (2-pyridyldithio)-PEG1-hydrazine linker serves as a valuable tool in the development of targeted chemotherapeutic agents for cancer treatment.
市场产品/服务共显示5个结果
- 供应商TargetMol规格货期5日内发货纯度-¥ 497.001
- 供应商PharmaBlock规格货期4-7周纯度-待询1
- 供应商Enamine规格货期4-6周纯度-¥ 251.001
- 供应商BIONET-Key Organics规格货期4-6周纯度-¥ 2,587.001
- 供应商Apollo规格货期4-6周纯度-待询1
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