Name: Pomalidomide-C7-COOH
Rating: 5 (10 reviews)

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HIT ID:HIT213136052
Cas No:2225940-51-0
常用名:Pomalidomide-C7-COOH
别名:Pomalidomide-C7-COOH
IUPAC:8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}octanoic acid
IUPAC:8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}octanoic acid
InChI key:IJDAOSIFULSGHH-UHFFFAOYSA-N

分子式:C21H25N3O6
分子量:415.446
氢键供体数 (HBD):3
氢键受体数 (HBA):7
LogP:2.335
SMILES:OC(=O)CCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
SMILES:OC(=O)CCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Pomalidomide-C7-COOH is a chemically synthesized E3 ligase cereblon ligand-linker conjugate, utilized as an intermediate compound for the synthesis of PROTAC BCL-XL degraders.

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