Name: Glyasperin F
Rating: 5 (10 reviews)

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HIT ID:HIT213884293
Cas No:145382-61-2
常用名:Glyasperin F
IUPAC:(3R)-5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-chromen-8-yl)-3,4-dihydro-2H-1-benzopyran-4-one
IUPAC:(3R)-5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-chromen-8-yl)-3,4-dihydro-2H-1-benzopyran-4-one
InChI key:CFCUNFSHJIQKLS-ZDUSSCGKSA-N

分子式:C20H18O6
分子量:354.358
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1(C)Oc2c(ccc(O)c2C=C1)[C@@H]1COc2cc(O)cc(O)c2C1=O |c:12|
SMILES:CC1(C)Oc2c(ccc(O)c2C=C1)[C@@H]1COc2cc(O)cc(O)c2C1=O |c:12|

Glyasperin F has antinociceptive, and anti-inflammatory effects, it could inhibit NO production in RAW 264.7 macrophages to some extent. Glyasperin F displayed cytotoxic effects against the four tested cancer cell lines with IC50values below 85 μM.

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