Name: 9-Hydroxycanthin-6-one
Rating: 5 (10 reviews)

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结构编辑

类似物检索

HIT ID:HIT213884428
Cas No:138544-91-9
常用名:9-Hydroxycanthin-6-one
IUPAC:13-hydroxy-1,6-diazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-3,5,7,9(16),10(15),11,13-heptaen-2-one
IUPAC:13-hydroxy-1,6-diazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-3,5,7,9(16),10(15),11,13-heptaen-2-one
InChI key:JHPIJMUNSMWWAA-UHFFFAOYSA-N

分子式:C14H8N2O2
分子量:236.23
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Oc1ccc2c3ccnc4ccc(=O)n(c2c1)c34
SMILES:Oc1ccc2c3ccnc4ccc(=O)n(c2c1)c34

9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilization.9-Hydroxycanthin-6-one inhibits Wnt signaling through the activation of GSK3β independent of CK1α.

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