Name: Oxychelerythrine
Rating: 5 (10 reviews)

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HIT ID:HIT213884860
Cas No:28342-33-8
常用名:Oxychelerythrine
IUPAC:17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13),2(10),3,8,11,14(19),15,17-octaen-20-one
IUPAC:17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13),2(10),3,8,11,14(19),15,17-octaen-20-one
InChI key:IHTXRYTWDARUKX-UHFFFAOYSA-N

分子式:C21H17NO5
分子量:363.369
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:2.901
SMILES:COc1ccc2c3ccc4cc5OCOc5cc4c3n(C)c(=O)c2c1OC
SMILES:COc1ccc2c3ccc4cc5OCOc5cc4c3n(C)c(=O)c2c1OC

Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 192.32 ppm. enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold.

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