Name: Chlorophorin
Rating: 5 (10 reviews)

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HIT ID:HIT213884891
Cas No:537-41-7
常用名:Chlorophorin
IUPAC:5-[(1E)-2-(2,4-dihydroxyphenyl)ethenyl]-2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]benzene-1,3-diol
IUPAC:5-[(1E)-2-(2,4-dihydroxyphenyl)ethenyl]-2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]benzene-1,3-diol
InChI key:OEILZVSHVTYHKL-MZYNZGBKSA-N

分子式:C24H28O4
分子量:380.484
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(\[#6]=[#6]\c2ccc(-[#8])cc2-[#8])cc1-[#8]
SMILES:[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(\[#6]=[#6]\c2ccc(-[#8])cc2-[#8])cc1-[#8]

Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM; it inhibits α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.

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