Name: Furowanin A
Rating: 5 (10 reviews)

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类似物检索

HIT ID:HIT213885138
Cas No:911004-72-3
常用名:Furowanin A
IUPAC:6-(3,4-dihydroxyphenyl)-4-hydroxy-2-(2-hydroxypropan-2-yl)-9-(3-methylbut-2-en-1-yl)-2H,3H,5H-furo[3,2-g]chromen-5-one
IUPAC:6-(3,4-dihydroxyphenyl)-4-hydroxy-2-(2-hydroxypropan-2-yl)-9-(3-methylbut-2-en-1-yl)-2H,3H,5H-furo[3,2-g]chromen-5-one
InChI key:NMEQUFXTRAXRGN-UHFFFAOYSA-N

分子式:C25H26O7
分子量:438.476
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[#6]\[#6](-[#6])=[#6]\[#6]-c1c2-[#8]-[#6](-[#6]-c2c(-[#8])c2c1occ(-c1ccc(-[#8])c(-[#8])c1)c2=O)C([#6])([#6])[#8]
SMILES:[#6]\[#6](-[#6])=[#6]\[#6]-c1c2-[#8]-[#6](-[#6]-c2c(-[#8])c2c1occ(-c1ccc(-[#8])c(-[#8])c1)c2=O)C([#6])([#6])[#8]

Furowanin A shows significant cytotoxicity against HL-60 cells, it induces that Caspase-9 and caspase-3 inhibitors suppresses apoptosis.

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