Name: Dodoviscin A
Rating: 5 (10 reviews)

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HIT ID:HIT213885196
Cas No:1372527-25-7
常用名:Dodoviscin A
IUPAC:5,7-dihydroxy-2-[4-hydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl)-5-(4-hydroxy-3-methylbutyl)phenyl]-3,6-dimethoxy-4H-chromen-4-one
IUPAC:5,7-dihydroxy-2-[4-hydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl)-5-(4-hydroxy-3-methylbutyl)phenyl]-3,6-dimethoxy-4H-chromen-4-one
InChI key:JOFIZXLDARFSIK-UHFFFAOYSA-N

分子式:C27H32O9
分子量:500.544
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:COc1c(O)cc2oc(-c3cc(CCC(C)CO)c(O)c(CC(O)C(C)=C)c3)c(OC)c(=O)c2c1O
SMILES:COc1c(O)cc2oc(-c3cc(CCC(C)CO)c(O)c(CC(O)C(C)=C)c3)c(OC)c(=O)c2c1O

Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells, it can enhance the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4.

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