Name: Hedycoronen A
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT213885606
Cas No:1383441-73-3
常用名:Hedycoronen A
IUPAC:3-[(1E)-2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl]ethenyl]-5-methoxy-2,5-dihydrofuran-2-one
IUPAC:3-[(1E)-2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl]ethenyl]-5-methoxy-2,5-dihydrofuran-2-one
InChI key:BQAWJLFWEBGZIH-MZBNRDNVSA-N

分子式:C21H30O3
分子量:330.468
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:COC1OC(=O)C(\C=C\[C@H]2C(=C)CC[C@H]3C(C)(C)CCC[C@]23C)=C1 |c:24|
SMILES:COC1OC(=O)C(\C=C\[C@H]2C(=C)CC[C@H]3C(C)(C)CCC[C@]23C)=C1 |c:24|

Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC(50) ranging from 4.1±0.2 to 9.1±0.3 uM, they also show moderate inhibitory activity on the tumor necrosis factor-α (TNF-α) production with IC(50) values of 46.0±1.3 and 12.7±0.3 uM.

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~