Name: Leojaponin
Rating: 5 (10 reviews)

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HIT ID:HIT213885801
Cas No:864817-63-0
常用名:Leojaponin
IUPAC:(4aR)-4-[2-(furan-3-yl)ethyl]-1-hydroxy-3,4a,8,8-tetramethyl-2,4a,5,6,7,8-hexahydronaphthalen-2-one
IUPAC:(4aR)-4-[2-(furan-3-yl)ethyl]-1-hydroxy-3,4a,8,8-tetramethyl-2,4a,5,6,7,8-hexahydronaphthalen-2-one
InChI key:OOJGVMFNPNJNFV-HXUWFJFHSA-N

分子式:C20H26O3
分子量:314.425
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1=C(CCc2ccoc2)[C@@]2(C)CCCC(C)(C)C2=C(O)C1=O |c:1,t:20|
SMILES:CC1=C(CCc2ccoc2)[C@@]2(C)CCCC(C)(C)C2=C(O)C1=O |c:1,t:20|

Leojaponin is a prolyl oligopeptidase (POP) inhibitor. Leojaponin exhibits significant cytoprotective activities against glutamate-induced toxicity at concentrations ranging from 0.1 microm to 10 microm.

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