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HIT213886021
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HIT213886021
  • HIT ID:HIT213886021
  • Cas No:1146113-27-0
  • 常用名:Moracin T
  • IUPAC:5-[6-hydroxy-5-methoxy-4-(3-methylbut-2-en-1-yl)-1-benzofuran-2-yl]benzene-1,3-diol
    IUPAC:5-[6-hydroxy-5-methoxy-4-(3-methylbut-2-en-1-yl)-1-benzofuran-2-yl]benzene-1,3-diol
  • InChI key:BILBQNGVYFSUOZ-UHFFFAOYSA-N
  • 分子式:C20H20O5
  • 分子量:340.375
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[#6]-[#8]-c1c(-[#8])cc2oc(cc2c1-[#6]\[#6]=[#6](/[#6])-[#6])-c1cc(-[#8])cc(-[#8])c1
    SMILES:[#6]-[#8]-c1c(-[#8])cc2oc(cc2c1-[#6]\[#6]=[#6](/[#6])-[#6])-c1cc(-[#8])cc(-[#8])c1
  • Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermore can significantly suppress the elevation in 4-HNE level and elevate expression of c-fos, c-myc and cycloxygenase-2 (COX-2) in normal epidermis induced by double application of TPA; the moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
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    TargetMolSC
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    ¥ 5,230.00
    1

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