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  3. HIT213886621
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HIT213886621
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HIT213886621
  • HIT ID:HIT213886621
  • Cas No:126724-95-6
  • 常用名:Tilifodiolide
  • IUPAC:3-[(1R,8S)-1-(furan-3-yl)-3-oxo-1H,3H,6H,7H,8H,9H-naphtho[1,2-c]furan-8-yl]-2,5-dihydrofuran-2-one
    IUPAC:3-[(1R,8S)-1-(furan-3-yl)-3-oxo-1H,3H,6H,7H,8H,9H-naphtho[1,2-c]furan-8-yl]-2,5-dihydrofuran-2-one
  • InChI key:GBTJKEKFEUNDHY-SGTLLEGYSA-N
  • 分子式:C20H16O5
  • 分子量:336.343
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:O=C1OCC=C1[C@H]1CCc2ccc3C(=O)O[C@@H](c4ccoc4)c3c2C1 |c:4|
    SMILES:O=C1OCC=C1[C@H]1CCc2ccc3C(=O)O[C@@H](c4ccoc4)c3c2C1 |c:4|
  • Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    纯度
    -
    ¥ 4,040.00
    1
  • 供应商
    AnyMoleSC
    规格
    货期
    纯度
    -
    ¥ 4,250.00
    1

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