Name: Ailanthoidol
Rating: 5 (10 reviews)

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HIT ID:HIT213887171
Cas No:156398-61-7
常用名:Ailanthoidol
IUPAC:4-{5-[(1E)-3-hydroxyprop-1-en-1-yl]-7-methoxy-1-benzofuran-2-yl}-2-methoxyphenol
IUPAC:4-{5-[(1E)-3-hydroxyprop-1-en-1-yl]-7-methoxy-1-benzofuran-2-yl}-2-methoxyphenol
InChI key:ZDQCRQVGMKIBPN-ONEGZZNKSA-N

分子式:C19H18O5
分子量:326.348
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:COc1cc(ccc1O)-c1cc2cc(\C=C\CO)cc(OC)c2o1
SMILES:COc1cc(ccc1O)-c1cc2cc(\C=C\CO)cc(OC)c2o1

Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potential as a chemopreventive agent against tumor promotion. Ailanthoidol has anti-adipogenic activity, it effectively suppresses adipogenesis and that it exerts its role mainly through the significant down-regulation of PPARγ and C/EBPα expression.

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