Name: Lenalidomide-4-aminomethyl hydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT213953492
Cas No:444289-05-8
常用名:Lenalidomide-4-aminomethyl hydrochloride
常用名:Lenalidomide-4-aminomethyl hydrochloride
IUPAC:3-[4-(aminomethyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione hydrochloride
IUPAC:3-[4-(aminomethyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione hydrochloride
InChI key:VOUMCDUUDATPTJ-UHFFFAOYSA-N

分子式:C14H16ClN3O3
分子量:309.75
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:-0.743
SMILES:Cl.NCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
SMILES:Cl.NCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

Lenalidomide-4-aminomethyl hydrochloride is a compound derived from Lenalidomide, serving as a cereblon (CRBN) ligand for the recruitment of CRBN protein. By connecting Lenalidomide-4-aminomethyl hydrochloride to the ligand via a linker, PROTAC formation can be facilitated.

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