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HIT214314806
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HIT214314806
  • HIT ID:HIT214314806
  • Cas No:1225433-96-4
  • 常用名:cIAP1 Ligand-Linker Conjugates 15
    常用名:cIAP1 Ligand-Linker Conjugates 15
  • 别名:E3 ligase Ligand-Linker Conjugates 34
  • IUPAC:2-[2-(2-aminoethoxy)ethoxy]ethyl (2S)-2-[(2S,3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoate
    IUPAC:2-[2-(2-aminoethoxy)ethoxy]ethyl (2S)-2-[(2S,3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoate
  • InChI key:YRJDBNNKOCUVLA-WKNISULPSA-N
  • 分子式:C37H47N3O8
  • 分子量:661.796
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)OCCOCCOCCN
    SMILES:CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)OCCOCCOCCN
  • cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1].
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    TargetMolSC
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