Name: TCO-PEG2-amine
Rating: 5 (10 reviews)

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HIT ID:HIT214314850
Cas No:2141981-87-3
常用名:TCO-PEG2-amine
IUPAC:cyclooct-4-en-1-yl N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate
IUPAC:cyclooct-4-en-1-yl N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate
InChI key:XCPPYCGUCZZMQS-UHFFFAOYSA-N

分子式:C15H28N2O4
分子量:300.399
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:NCCOCCOCCNC(=O)OC1CCCC=CCC1 |w:18.18|
SMILES:NCCOCCOCCNC(=O)OC1CCCC=CCC1 |w:18.18|

TCO-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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