Name: TCO-PEG8-amine
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT214314858
Cas No:2353409-92-2
常用名:TCO-PEG8-amine
IUPAC:cyclooct-4-en-1-yl N-(26-amino-3,6,9,12,15,18,21,24-octaoxahexacosan-1-yl)carbamate
IUPAC:cyclooct-4-en-1-yl N-(26-amino-3,6,9,12,15,18,21,24-octaoxahexacosan-1-yl)carbamate
InChI key:MXEGVNVGOKEYSH-UHFFFAOYSA-N

分子式:C27H52N2O10
分子量:564.717
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC1CCCC=CCC1 |w:36.36|
SMILES:NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC1CCCC=CCC1 |w:36.36|

TCO-PEG8-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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