Name: Acid-PEG5-TEMPO
Rating: 5 (10 reviews)

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结构编辑

类似物检索

HIT ID:HIT214314872
Cas No:2055040-79-2
常用名:Acid-PEG5-TEMPO
IUPAC:[4-(1-carboxy-3,6,9,12,15-pentaoxaoctadecan-18-amido)-2,2,6,6-tetramethylpiperidin-1-yl]oxidanyl
IUPAC:[4-(1-carboxy-3,6,9,12,15-pentaoxaoctadecan-18-amido)-2,2,6,6-tetramethylpiperidin-1-yl]oxidanyl
InChI key:UGFYUXWUXOOSOD-UHFFFAOYSA-N

分子式:C23H43N2O9
分子量:491.602
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCOCCOCCOCCOCCOCCC(O)=O |^1:10|
SMILES:CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCOCCOCCOCCOCCOCCC(O)=O |^1:10|

Acid-PEG5-TEMPO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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