Name: Foliglurax monohydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT214315068
Cas No:2133294-96-7
常用名:Foliglurax monohydrochloride
别名:PXT002331 (monohydrochloride)
IUPAC:N-{6-[3-(morpholin-4-yl)propyl]-2-{thieno[3,2-c]pyridin-6-yl}-4H-chromen-4-ylidene}hydroxylamine hydrochloride
IUPAC:N-{6-[3-(morpholin-4-yl)propyl]-2-{thieno[3,2-c]pyridin-6-yl}-4H-chromen-4-ylidene}hydroxylamine hydrochloride
InChI key:LOBGNYCFXPNFJB-UHFFFAOYSA-N

分子式:C23H24ClN3O3S
分子量:457.97
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cl.ON=c1cc(oc2ccc(CCCN3CCOCC3)cc12)-c1cc2sccc2cn1 |w:2.0|
SMILES:Cl.ON=c1cc(oc2ccc(CCCN3CCOCC3)cc12)-c1cc2sccc2cn1 |w:2.0|

Foliglurax monohydrochloride Antiparkinsonian effect. is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM.

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