Name: FTI-2148 diTFA
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214315075
Cas No:817586-01-9
常用名:FTI-2148 diTFA
IUPAC:(2S)-2-{[5-({[(1H-imidazol-5-yl)methyl]amino}methyl)-2'-methyl-[1,1'-biphenyl]-2-yl]formamido}-4-(methylsulfanyl)butanoic acid; trifluoroacetic acid
IUPAC:(2S)-2-{[5-({[(1H-imidazol-5-yl)methyl]amino}methyl)-2'-methyl-[1,1'-biphenyl]-2-yl]formamido}-4-(methylsulfanyl)butanoic acid; trifluoroacetic acid
InChI key:ZCCUFUPJNUTGJM-FTBISJDPSA-N

分子式:C26H29F3N4O5S
分子量:566.6
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(O)=O
SMILES:OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(O)=O

FTI-2148 diTFA is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 1.4 nM and 1.7 μM, respectively.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~