Name: Gemcabene calcium
Rating: 5 (10 reviews)

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HIT ID:HIT214315087
Cas No:209789-08-2
常用名:Gemcabene calcium
别名:PD-72953 calcium
IUPAC:6-[(5-carboxy-5,5-dimethylpentyl)oxy]-2,2-dimethylhexanoic acid calcium dihydride
IUPAC:6-[(5-carboxy-5,5-dimethylpentyl)oxy]-2,2-dimethylhexanoic acid calcium dihydride
InChI key:XQBIOMIODKXEGV-UHFFFAOYSA-N

分子式:C16H30CaO5
分子量:342.489
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[CaH2].CC(C)(CCCCOCCCCC(C)(C)C(O)=O)C(O)=O
SMILES:[CaH2].CC(C)(CCCCOCCCCC(C)(C)C(O)=O)C(O)=O

Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).

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