Name: FM-479
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214315398
Cas No:2226521-64-6
常用名:FM-479
IUPAC:2-cyano-3-(5-{3-cyclohexyl-10-methyl-3,5,8,10-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}furan-2-yl)-N,N-dimethylprop-2-enamide
IUPAC:2-cyano-3-(5-{3-cyclohexyl-10-methyl-3,5,8,10-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl}furan-2-yl)-N,N-dimethylprop-2-enamide
InChI key:RPIGHLXKDWUGDT-UHFFFAOYSA-N

分子式:C25H26N6O2
分子量:442.523
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CN(C)C(=O)C(=Cc1ccc(o1)-c1nc2cnc3n(C)ccc3c2n1C1CCCCC1)C#N |w:6.6|
SMILES:CN(C)C(=O)C(=Cc1ccc(o1)-c1nc2cnc3n(C)ccc3c2n1C1CCCCC1)C#N |w:6.6|

FM-479, an FM-381 structural analog, exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range (100-300 nM). FM-479 is used as a negative control for FM-381.

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