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HIT214315792
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HIT214315792
  • HIT ID:HIT214315792
  • Cas No:119188-37-3
  • 常用名:Coronarin D
  • IUPAC:3-[2-(5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl)ethylidene]-5-hydroxyoxolan-2-one
    IUPAC:3-[2-(5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl)ethylidene]-5-hydroxyoxolan-2-one
  • InChI key:DYYYQLXAGIXUGM-UHFFFAOYSA-N
  • 分子式:C20H30O3
  • 分子量:318.457
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC1(C)CCCC2(C)C(CC=C3CC(O)OC3=O)C(=C)CCC12 |w:10.9|
    SMILES:CC1(C)CCCC2(C)C(CC=C3CC(O)OC3=O)C(=C)CCC12 |w:10.9|
  • Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases.Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    5日内发货
    纯度
    -
    ¥ 12,500.00
    1
  • 供应商
    AnyMoleSC
    规格
    货期
    纯度
    -
    待询
    1

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