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  3. HIT214315966
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HIT214315966
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HIT214315966
  • HIT ID:HIT214315966
  • Cas No:57566-47-9
  • 常用名:Isofuranodiene
  • IUPAC:3,6,10-trimethyl-4H,7H,8H,11H-cyclodeca[b]furan
    IUPAC:3,6,10-trimethyl-4H,7H,8H,11H-cyclodeca[b]furan
  • InChI key:VMDXHYHOJPKFEK-IAVOFVOCSA-N
  • 分子式:C15H20O
  • 分子量:216.324
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cc1coc2C\C(C)=C\CC\C(C)=C\Cc12 |t:7,12|
    SMILES:Cc1coc2C\C(C)=C\CC\C(C)=C\Cc12 |t:7,12|
  • Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells; it can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents. Isofuranodiene at concentrations of 25 and 12.5 lM alone, or in combination with 50 nM nerve growth factor (NGF) , shows a marked stimulation of neuritogenesis,which appears to be a promising neurotrophic and neuroprotective agent.
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  • 供应商
    TargetMolSC
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    ¥ 2,760.00
    1

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