Name: Teuclatriol
Rating: 5 (10 reviews)

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HIT ID:HIT214316231
Cas No:152110-17-3
常用名:Teuclatriol
IUPAC:(1S,3aR,4R,8R,8aR)-1,4-dimethyl-7-(propan-2-yl)-decahydroazulene-1,4,8-triol
IUPAC:(1S,3aR,4R,8R,8aR)-1,4-dimethyl-7-(propan-2-yl)-decahydroazulene-1,4,8-triol
InChI key:CXQOZINRAFPQEX-CIJFKWAFSA-N

分子式:C15H28O3
分子量:256.386
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@@]12CC[C@](C)(O)[C@@]1([H])[C@H](O)C(CC[C@@]2(C)O)C(C)C |@@:17|
SMILES:[H][C@@]12CC[C@](C)(O)[C@@]1([H])[C@H](O)C(CC[C@@]2(C)O)C(C)C |@@:17|

Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-ÎºB signaling at doses of 312µM and higher. It showed a significant anti-proliferative effect on human activated-peripheral blood lymphocytes (IC50, 72.8 ± 5.4 µg/ml).

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