Name: Ceftizoxime Sodium
Rating: 5 (10 reviews)

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HIT ID:HIT214316402
Cas No:68401-82-1
常用名:Ceftizoxime Sodium
别名:头孢唑肟钠, Monosodium Salt, Ceftizoxime, Eposerin, Epocelin, Ceftizoxim-natrium, Ceftizoxime sodium salt, Cefizox
别名:头孢唑肟钠, Monosodium Salt, Ceftizoxime, Eposerin, Epocelin, Ceftizoxim-natrium, Ceftizoxime sodium salt, Cefizox
IUPAC:(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium
IUPAC:(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium
InChI key:LNJZODVQDGCASS-LIGXYSTNSA-N

分子式:C13H13N5NaO5S2
分子量:406.39
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[Na].[H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O |c:4|
SMILES:[Na].[H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O |c:4|

Ceftizoxime, a third-generation cephalosporin effective against Gram-negative and Gram-positive bacteria, binds penicillin-binding proteins (PBPs) to inhibit the bacterial cell wall synthesis. It rather resembles cefotaxime in its properties but is not subject to metabolism.

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