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  3. HIT214316778
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HIT214316778
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HIT214316778
  • HIT ID:HIT214316778
  • Cas No:58880-43-6
  • 常用名:Cridanimod sodium
  • 别名:XBIO-101, XBIO101, XBIO 101, Sodium Cridanimod, Cycloferon, Cridanimod Na
    别名:XBIO-101, XBIO101, XBIO 101, Sodium Cridanimod, Cycloferon, Cridanimod Na
  • IUPAC:2-(9-oxo-9,10-dihydroacridin-10-yl)acetic acid sodium
    IUPAC:2-(9-oxo-9,10-dihydroacridin-10-yl)acetic acid sodium
  • InChI key:DTBMZZDVZAZJNU-UHFFFAOYSA-N
  • 分子式:C15H11NNaO3
  • 分子量:276.247
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[Na].OC(=O)Cn1c2ccccc2c(=O)c2ccccc12jcExt:v:0:0
    SMILES:[Na].OC(=O)Cn1c2ccccc2c(=O)c2ccccc12jcExt:v:0:0
  • Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 812.00
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