Name: Demethoxyfumitremorgin C
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214317156
Cas No:111768-16-2
常用名:Demethoxyfumitremorgin C
IUPAC:(1S,12S,15S)-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{15,19}]icosa-3(11),4,6,8-tetraene-14,20-dione
IUPAC:(1S,12S,15S)-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{15,19}]icosa-3(11),4,6,8-tetraene-14,20-dione
InChI key:LQXCSIKDOISJTI-BZSNNMDCSA-N

分子式:C21H23N3O2
分子量:349.434
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@@]12CCCN1C(=O)[C@]1([H])Cc3c([nH]c4ccccc34)[C@H](C=C(C)C)N1C2=O |wU:1.0,8.9,wD:20.23,(-6.13,-6.74,;-5.74,-5.25,;-7.26,-5.51,;-7.97,-4.14,;-6.89,-3.04,;-5.51,-3.73,;-4.08,-3.17,;-3.85,-1.64,;-2.87,-4.13,;-2.64,-2.6,;-1.44,-3.56,;-.23,-4.52,;-.46,-6.04,;.91,-6.73,;1.99,-5.63,;3.53,-5.7,;4.36,-4.4,;3.65,-3.04,;2.11,-2.97,;1.28,-4.27,;-1.9,-6.61,;-2.12,-8.13,;-.92,-9.09,;-1.15,-10.61,;.51,-8.53,;-3.1,-5.65,;-4.53,-6.21,;-4.76,-7.74,)|
SMILES:[H][C@@]12CCCN1C(=O)[C@]1([H])Cc3c([nH]c4ccccc34)[C@H](C=C(C)C)N1C2=O |wU:1.0,8.9,wD:20.23,(-6.13,-6.74,;-5.74,-5.25,;-7.26,-5.51,;-7.97,-4.14,;-6.89,-3.04,;-5.51,-3.73,;-4.08,-3.17,;-3.85,-1.64,;-2.87,-4.13,;-2.64,-2.6,;-1.44,-3.56,;-.23,-4.52,;-.46,-6.04,;.91,-6.73,;1.99,-5.63,;3.53,-5.7,;4.36,-4.4,;3.65,-3.04,;2.11,-2.97,;1.28,-4.27,;-1.9,-6.61,;-2.12,-8.13,;-.92,-9.09,;-1.15,-10.61,;.51,-8.53,;-3.1,-5.65,;-4.53,-6.21,;-4.76,-7.74,)|

Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer.

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~