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  3. HIT214317472
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HIT214317472
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HIT214317472
  • HIT ID:HIT214317472
  • Cas No:1204416-85-2
  • 常用名:QAQ dichloride
  • IUPAC:triethyl({[4-(2-{4-[2-(triethylazaniumyl)acetamido]phenyl}diazen-1-yl)phenyl]carbamoyl}methyl)azanium
    IUPAC:triethyl({[4-(2-{4-[2-(triethylazaniumyl)acetamido]phenyl}diazen-1-yl)phenyl]carbamoyl}methyl)azanium
  • InChI key:PMJGZQTXCKBQOV-UHFFFAOYSA-P
  • 分子式:C28H44N6O2
  • 分子量:496.699
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC[N+](CC)(CC)CC(=O)Nc1ccc(cc1)N=Nc1ccc(NC(=O)C[N+](CC)(CC)CC)cc1 |w:18.19|
    SMILES:CC[N+](CC)(CC)CC(=O)Nc1ccc(cc1)N=Nc1ccc(NC(=O)C[N+](CC)(CC)CC)cc1 |w:18.19|
  • QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit this effect. This compound is membrane-impermeant and selectively enters pain-sensing neurons expressing endogenous import channels. QAQ dichloride functions as a light-sensitive analgesic and provides a valuable tool for investigating signaling mechanisms involved in acute and chronic pain [1] [2].
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  • 供应商
    TargetMolSC
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    货期
    5日内发货
    纯度
    -
    ¥ 720.00
    1

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