Name: AZD-3289
Rating: 5 (10 reviews)

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HIT ID:HIT214318286
Cas No:1227163-49-6
常用名:AZD-3289
别名:AZD 3289
IUPAC:(1S)-4-fluoro-1-[4-fluoro-3-(pyrimidin-5-yl)phenyl]-1-[2-(trifluoromethyl)pyridin-4-yl]-1H-isoindol-3-amine
IUPAC:(1S)-4-fluoro-1-[4-fluoro-3-(pyrimidin-5-yl)phenyl]-1-[2-(trifluoromethyl)pyridin-4-yl]-1H-isoindol-3-amine
InChI key:UDQUVXUVXUGJFO-QHCPKHFHSA-N

分子式:C24H14F5N5
分子量:467.403
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:NC1=N[C@](c2cccc(F)c12)(c1ccnc(c1)C(F)(F)F)c1ccc(F)c(c1)-c1cncnc1 |t:1|
SMILES:NC1=N[C@](c2cccc(F)c12)(c1ccnc(c1)C(F)(F)F)c1ccc(F)c(c1)-c1cncnc1 |t:1|

AZD-3289, a potent BACE1 inhibitor, is used potentially for the treatment of Alzheimer's disease.

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