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  3. HIT214318628
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HIT214318628
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HIT214318628
  • HIT ID:HIT214318628
  • Cas No:2448-68-2
  • 常用名:Pipamperone HCl
  • 别名:R4050 HCl, Pipamperone hydrochloride, floropipamide hydrochloride, floropipamide HCl, carpiperone
    别名:R4050 HCl, Pipamperone hydrochloride, floropipamide hydrochloride, floropipamide HCl, carpiperone
  • IUPAC:1'-[4-(4-fluorophenyl)-4-oxobutyl]-[1,4'-bipiperidine]-4'-carboxamide hydrochloride
    IUPAC:1'-[4-(4-fluorophenyl)-4-oxobutyl]-[1,4'-bipiperidine]-4'-carboxamide hydrochloride
  • InChI key:UBQRWZFMJULMLP-UHFFFAOYSA-N
  • 分子式:C21H31ClFN3O2
  • 分子量:411.95
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cl.NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1
    SMILES:Cl.NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1
  • Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. It shows much higher affinity for the 5-HT2A and D4 receptors over the D2 receptor (15-fold in the case of the D4 receptor, and even higher in the case of the 5-HT2A receptor), being regarded as "highly selective" for the former two sites at low doses. Pipamperone has low and likely insignificant affinity for the H1 and mACh receptors, as well as for other serotonin and dopamine receptors.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    1-2周
    纯度
    -
    ¥ 10,600.00
    1

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