Name: SM-130686
Rating: 5 (10 reviews)

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HIT ID:HIT214318719
Cas No:259667-25-9
常用名:SM-130686
别名:SM130,686, SM 130686, SM 130,686
IUPAC:(3S)-3-(2-chlorophenyl)-1-[2-(diethylamino)ethyl]-3-hydroxy-2-oxo-4-(trifluoromethyl)-2,3-dihydro-1H-indole-6-carboxamide hydrochloride
IUPAC:(3S)-3-(2-chlorophenyl)-1-[2-(diethylamino)ethyl]-3-hydroxy-2-oxo-4-(trifluoromethyl)-2,3-dihydro-1H-indole-6-carboxamide hydrochloride
InChI key:RRHATDIHSDLAOM-ZMBIFBSDSA-N

分子式:C22H24Cl2F3N3O3
分子量:506.35
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cl.CCN(CC)CCN1C(=O)[C@](O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1Cl
SMILES:Cl.CCN(CC)CCN1C(=O)[C@](O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1Cl

SM-130,686 is a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue. It has around half the potency of the endogenous agonist ghrelin as a stimulator of growth hormone release.

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