Name: SU9518
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT214318732
Cas No:251356-32-8
常用名:SU9518
别名:SU-9518, SU 9518, 5-Br-SU6668, 5BrSU6668, 5 Br SU6668
别名:SU-9518, SU 9518, 5-Br-SU6668, 5BrSU6668, 5 Br SU6668
IUPAC:3-{5-[(5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrol-3-yl}propanoic acid
IUPAC:3-{5-[(5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrol-3-yl}propanoic acid
InChI key:CQXPYMNBBOWLME-UHFFFAOYSA-N

分子式:C18H17BrN2O3
分子量:389.249
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cc1[nH]c(C=C2C(=O)Nc3ccc(Br)cc23)c(C)c1CCC(O)=O |w:4.3|
SMILES:Cc1[nH]c(C=C2C(=O)Nc3ccc(Br)cc23)c(C)c1CCC(O)=O |w:4.3|

SU9518, a tyrosine kinase inhibitor with PDGFRα specificity, can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Müller cell rabbit models.

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